fibrin degradation products การใช้

• Often, fibrin degradation product levels are determined, which can be elevated.
• Thrombin time can be prolonged by heparin, fibrin degradation products, and fibrinogen deficiency or abnormality.
• Patients uniformly show severe thrombocytopenia, low fibrinogen levels, high fibrin degradation products ( due to fibrinolysis ), and microangiopathic hemolysis.
• Plasmin, in addition to lysing fibrin clots, also cleaves the complement system component C3, and fibrin degradation products have some vascular permeability inducing effects.
• Five hours after being bitten, his blood had a normal platelet count, but was incoagulable with a reduced fibrinogen concentration, elevated fibrin degradation products and D-dimer.
• Burnand is looking for funding to test blood samples from 1, 000 long-haul passengers for fibrin degradation products, a sign of possible trouble, before and after their flights.
• The resultant fragments, " high molecular weight polymers ", are digested several times more by plasmin to lead to intermediate and then to small polymers ( fibrin degradation products or FDPs ).
• The diagnosis of hyperfibrinolysis is made indirectly with immunochemical methods which detect the elevation of biomarkers such as D-Dimer ( cross-linked fibrin degradation products ), fibrinogen split products ( FSP ), complexes of plasmin and alpha-2-antiplasmin ( PAP ).
• In contrast with typical disseminated intravascular coagulation seen with other causes of septicemia and occasionally with advanced cancer, coagulation factors are not consumed in HUS ( or TTP ) and the coagulation screen, fibrinogen level, and assays for fibrin degradation products such as " D-Dimers ", are generally normal despite the low platelet count ( thrombocytopenia ).